This course is a continuation of DPT 840: Clinical Medicine and Pathology II, the second of two courses with emphasis on neuromuscular pathology and diagnosis. This course is designed to continue to challenge the student to evaluate the knowledge of basic clinical presentations associated with neuromuscular pathology as a foundation for direct patient care and research. Additionally, students will be challenged to evaluate the knowledge of clinical presentations associated with the neuromuscular system as a foundation for direct patient/client care and research. During the semester, students will investigate similarly presenting neuromuscular diagnoses and, through clinical evaluation and physiological presentation, will demonstrate their ability to provide the appropriate prognosis and desired medical and therapeutic interventions given the diagnosis. Topics will correspond with the diagnoses and neuromuscular pathologies being discussed concurrently in DPT 831: Neuromuscular Examination and Rehabilitation II. Characteristics of common neuromuscular pathologies will be addressed, including physiology, etiology; epidemiology; underlying pathophysiology and histology; clinical signs and symptoms related impairments, activity, and participation limitations; natural history and prognosis; diagnostic medical procedures; differential diagnosis; medical, pharmacological, and surgical management; and expected outcomes. Differential diagnosis related to neuromuscular pathology will be emphasized and applied to determine appropriateness of physical therapy intervention. This course also incorporates the evidence-based practice model in decision making for complex situations. Content presented will encompass pathologies observed across multiple neuromuscular conditions and points of time in the lifespan.