This collaboration and laboratory course is the second of two courses that will teach the student the foundational elements of musculoskeletal (MSK) examination, evaluation, and intervention as a foundation for direct patient care. Students will actively learn the components for safe and effective MSK examination, evaluation, and intervention of the lower quarter within best evidence research. The lower quarter consists of the lower thoracic, lumbar, and sacral spinal regions, lower rib cage, and lower extremities. Key topics characteristic of common and prevalent MSK conditions, injuries, and pathologies will be addressed, including foundational and normal physiology; etiology; epidemiology; clinical signs and symptoms; impairments, functional limitations; differential diagnosis; interventions, including non-thrust and thrust joint mobilizations/manipulations; prognosis; and outcomes. Students will assemble psychomotor skills and develop critical thinking and clinical decision-making. Lastly, students will recognize conditions needing intra- and/or interprofessional referral.