This collaboration and laboratory course is the first of two courses that will focus on the foundational elements of musculoskeletal (MSK) examination, evaluation, and intervention as a foundation for direct patient care. Students will actively learn the components for safe and effective MSK examination, evaluation, and intervention of the upper quarter within best evidence research. The upper quarter consists of the head, temporomandibular joints, cervical and upper thoracic spinal regions, upper rib cage, and upper extremities. Key topics characteristic of common and prevalent MSK conditions, injuries, and pathologies will be addressed, including foundational and normal physiology; etiology; epidemiology; clinical signs and symptoms; impairments; functional limitations; differential diagnosis; interventions, including non-trust and thrust joint mobilizations/manipulations; prognosis; and outcomes. Students will assemble psychomotor skills and develop critical thinking and clinical decision-making. Lastly, students will recognize conditions needing intra- and/or interprofessional referral.